白眉蛇毒血凝酶局部治疗闭合性腹部损伤肝破裂的疗效

Clinical efficacy of the local treatment of liver rupture with blunt abdominal injury by homocoagulase injection

目的探讨白眉蛇毒血凝酶局部治疗闭合性腹部损伤肝破裂的方法,归纳其临床病症的特点和治疗手段。方法选取我院2009年9月～2011年8月收治的48例闭合性腹部损伤肝破裂患者进行分析。采用白眉蛇毒血凝酶注射方法治疗,局部治疗无效者采取手术方式。结果患者治愈44例,4例未能止血成功,采取手术治疗治愈。患者病前后指标有明显好转,差异有统计学意义(P<0.05)。结论白眉蛇毒血凝酶对于病情稳定较轻患者有良好的治疗作用,肝损伤严重者则需采用手术方式治疗。

OBJECTIVE To explore the local treatment of liver rupture with blunt abdominal injury by homocoagulase injection and summarize the clinical symptoms.METHODS 48 patients of hepatorrhexis were involved in our hospital during 2009.9～2011.8.All the patients were treated by homocoagulase injection.Invalid cases were treated by surgery.RESULTS 44 cases were cured by homocoagulase injection and 4 cases were cured by surgery.Patients′ clinical situations had great improvements and the differences of index was significant.CONCLUSION Homocoagulase injection treatment is available and effective to the stable cases with no other organ damages,while surgery treatment is suitable to those with severe liver injury.