甘草酸二铵与复方甘草酸单铵S氯化钠治疗药源性肝损害的成本-效益分析

Cost-effectiveness analysis of Diammonium glycyrrhizinate injection and compound ammonium glycyirhetate S and sodium chloride injection for Drug-induced liver injury

目的比较甘草酸二铵与复方甘草酸单铵S氯化钠治疗药源性肝损害的疗效及经济性,进行成本-效益分析。方法将64例患者随机分成两组:A组(甘草酸二铵注射液),B组(复方甘草酸单铵S氯化钠注射液)。结果 A、B两组的成本-效益比值分别为2.25元、7.88元。结论甘草酸二铵注射液治疗药源性肝损害更有效、更经济。

OBJECTIVE To compare the pharmacoeconomic effectiveness of two medicine for drug-induced liver injury.METHODS 64 patients with Drug-induced liver injury were divided into two groups：A group（Diammonium Glycyrrhizinate Injection）,B group（Compound Ammonium Glycyrrhetate S and Sodium Chloride Injection）.Evaluation was carried out with cost-effectiveness analysis.RESULTS The cost-effectiveness ratios of two groups were $2.25 and $7.88.CONCLUSION Diammonium Glycyrrhizinate was the better drug for Drug-induced liver injury.