米索前列醇预防产妇产后出血的临床观察

目的探讨米索前列醇预防产妇产后出血的临床疗效。方法将足月妊娠产妇120例随机分为观察组和对照组,每组60例。观察组在胎儿娩出后用缩宫素且立即口服米索前列醇500μg,对照组胎儿娩出后用缩宫素,观察并对比分析两组产中、产后出血量及血压、血红蛋白等。结果两组用药前后血压变化比较,差异无统计学意义(P>0.05),两组产后2h内平均出血量比较,差异有统计学意义(P<0.01),产后血红蛋白比较,差异有统计学意义(P<0.01)。结论使用米索前列醇联合缩宫素比单纯使用缩宫素更有效于预防产妇产后出血。

Objective To investigate the clinical efficacy of misoprostol to prevent postpartum bleeding.Methods Will be full-term pregnancy women（n=120）were randomly divided into observation group and control group（n=60 cases）.The observation group with oxytocin after the baby is delivered immediately oral misoprostol 500ug control group fetus with oxytocin.Observation and comparative analysis of two sets of production,post-partum blood loss and blood pressure,hemoglobin.Results Of changes in blood pressure in the two groups before and after treatment no significant differences（P0.05）,two groups of postpartum 2h mean blood loss was significantly different（P0.01）,significant differences in postpartum hemoglobin（P0.01）.Conclusion Misoprostol combined with oxytocin is more effective than the simple use of oxytocin in the prevention of maternal postpartum hemorrhage.