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转化生长因子β信号通路研究进展 被引量:10

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摘要 转化生长因子-β(transforming growth factor—β,TGF—β)是生长因子超家族中具有免疫负调控功能的一大类细胞因子家族。现已知,几乎体内所有的细胞均可分泌TGF—β并对TGF—β产生反应…;但有证据表明,Foxp3+调节性T细胞(Foxp3+Treg)是TGF—p的主要来源。
出处 《医学研究杂志》 2012年第10期5-9,共5页 Journal of Medical Research
基金 国家自然科学基金资助项目(30971192 81130035 81071545) 国家重点基础研究发展计划基金项目资助(2012CB518102)
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同被引文献112

  • 1王红林,王治伦,吴劲,考希宾,高艳.p38 MAPK信号转导通路参与NO诱导兔关节软骨细胞凋亡[J].中国地方病防治,2006,21(6):332-335. 被引量:5
  • 2胡东,张荣波.脂多糖对过敏性哮喘患者细胞因子分泌的影响[J].现代预防医学,2007,34(2):237-239. 被引量:2
  • 3邓德厚,沈小珩.祛风中药治疗过敏性疾病实验研究进展[J].中国中医药信息杂志,2007,14(8):92-94. 被引量:24
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  • 5TaylorAW.Review of the activation of TGF - p in immunity [J].JLeukoc Biol,2009,85(1):29-33.
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  • 7Tian M , Neil JR , Schiemann WP.Transforming growth Factor and the hallmarks of cancer [J].Cell Signal, 2011,23(6):951-962.
  • 8Nakagawa T,Li JH,Garcia G,et al. TGF-beta induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways[J]. Kidney Int,2004,66(2):605-613.
  • 9Gulubova bl, Manolova I, Ananiev J,et al.Relationship of TGF-131 and Smad7 expression with decreased dendritic cell infiltration in liver gastrointestinal cancer metastasis[J]. APMIS, 2013,121 ( 10):967-975.
  • 10Rao C,Lin SL, Wen H,et al. Crosstalk between canonical TGF-β/Smad? and Wnt/β-catenin signaling pathway [J]. Zhejiang Da Xue Xue Ban, 2013,42(5):591-596.

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