喉癌术后患者主观睡眠质量与抑郁状况的调查研究

Research of the Depression and Subjective Sleep Quality Status after Laryngectomy

目的了解喉癌术后患者睡眠及抑郁相关的生存质量。方法采用国际上广泛应用的匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)及宗氏抑郁自评量表(self-rating depression scale,SDS)对46例喉癌术后患者进行问卷调查,调查结果量化评分,并做统计学分析。结果 (1)患者抑郁发生率43.5%,SDS标准分比常模显著增高(P<0.01);抑郁的发生与年龄和学历有关(P<0.05,P<0.01)。(2)患者PSQI总分为7.11±3.97,比常模显著增高(P<0.01)。(3)抑郁和非抑郁组的PSQI总分有显著差异(P<0.01);睡眠障碍和非睡眠障碍组的SDS标准分有显著差异(P<0.01)。(4)SDS标准分与PSQI总分及睡眠质量因子、入睡时间因子、睡眠时间因子、睡眠效率因子、日间功能因子存在显著的相关性(r分别为0.739,0.433,0.660,0.549,0.430,0.765,P<0.01)。结论 (1)喉癌术后患者负面情绪显著且睡眠较差。(2)患者文化程度越高,年龄越小,则抑郁程度越重。(3)抑郁与睡眠之间紧密联系。(4)研究喉癌术后患者的生存质量是十分必要的,争取通过全面的干预作用,全面提高患者术后的生存质量。

Objective To understand the quality of life about sleep and depression after laryngectomy. Methods The worldwide known PSQI and SDS was used in this research to evaluate the quality of life of 46 laryngectomy patients. The results of questionnaires were analyzed statistically. Results （ 1 ） The incidence of depression in patients was 43.5% and SDS Standard score was significantly higher than the norm （P 〈 O. O1 ）. Age and education was in connection with the aceurring of depression （P 〈 0.05,P 〈 0.01 ）. （2）The total score in PSQI was 7.11 ＋ 3.97 and significantly higher than the norm （ P 〈 0.01 ）. （3） The total PSQI score in depressed group and non- depressed group was significantly different（ P 〈 O. 01 ）. The standard score of SDS in sleep disorder group and non- sleep disorder group was significantly different（P 〈 O. O1 ）. （4） There was a significant relationship among SDS and the total sleep and the factor of sleep quality,the factor of time of entrying to wake, the factor of sleep time, the factor of sleep efficiency, the factor of function during the day（ r ： O. 739,0. 433,0. 660,0. 549,0. 430, O. 765, P 〈 O. O1 ）. Conchlsion （ 1 ） The sleep quality of laryngectomy patients was poor and they were with negative mood. （2）The more severe depression was in the patients who achieved the higher educational level or the younger. （3） There was close relationship between the sleep and depression. （4） It is essential to study the quality of life in laryngectomy patients. We should improve the quality of life with a comprehensive intervention.