气囊滞留物清除时间与呼吸机相关性肺炎的相关性研究

The correlation study of the time of subglottic secretion drainage with ventilator-associated pneumonia

目的探讨清除气管导管气囊上滞留物的最佳时间。方法将94例气管插管行机械通气治疗48 h以上患者随机分为A、B、C三组,分别每4 h、8 h、12 h进行气囊上滞留物清除。结果 4 h组和8 h组呼吸机相关性肺炎发生率、病死率、机械通气时间均低于12 h组(P<0.05),4 h组和8 h组比较,各项指标差异无统计学意义(P>0.05)。结论 8 h清除气管导管气囊上滞留物能明显减少呼吸机相关性肺炎的发生,缩短机械通气时间,降低病死率,节约成本,为最佳清除时间。

Objective To explore the best time of the subglottic secretion drainage. Methods A total of 94 patients with endotracheal intubation and mechanical ventilation for over 48 hours were randomly divided into three groups of A, B and C. And 4 hours,8 hours and 12 hours intermittent subglottic secretion drainage were done respectively in group A, B and C. Results The incidence of ventilator - associated pneumonia, mortality, duration of mechanical ventilation in group 4 hours and group 8 hom.＇s were lower than those of 12 hours group （ P 〈 0.05 ）. The indicators were no significant difference between group 4 hours and group 8 hours （ P 〉 0.05 ）. Conclusion The 8 hours intermittent subglottie secretion drainage can significantly reduce the incidence of ventilator - associated pneumonia, minimize the duration of mechanical ventilation and mortality and save the costs, thus it is the best clearing time.