胃癌淋巴结转移的进展分析

Progress in Studies on Lymphatic Metastasis of Gastric Cancer

规范联合淋巴结清扫范围和数目是取得胃癌治疗较佳疗效的保障,淋巴结转移数目联合阴性淋巴结数目能够提高胃癌患者预后评估准确性。最新研究表明:1)淋巴结转移的数目是目前最佳的评估胃癌预后的淋巴结转移分期方式;2)规范的淋巴结清扫应该遵从清扫范围达到D2而清扫淋巴结数目不低于15枚;3)阴性淋巴结数目是一个新的评估胃癌患者预后的重要指标。本文针对淋巴结转移在胃癌治疗效果和预后评估中的新进展和观点作一适于临床胃癌诊治的概述。

Objective： Normalization of the appropriate extent of lymphadenectomy and number of metastasized lymph nodes ensures superior curative effects. Most studies related to variations in the classification of lymph node metastasis, extent of lymph node metastasis, and number of metastatic lymph nodes aim to draw conclusions for clinical applicability. 1） Classification based on the number of metastatic lymph nodes is the best classification of nodal metastasis for predicting gastric cancer prognosis; 2） Standard lymphad enectomy should be in accordance with D2 operation and include at least 15 dissected lymph nodes; 3） The number of negative lymph nodes is a new classification of nodal metastasis for the accurate assessment of the gastric cancer prognosis. We examined new view points and evaluated the progress of studies that focus on the treatment and prognostic assessment of gastric cancer in this review.