直肠癌术后同时性肝肺转移个体化治疗的个案分析

A Case Analysis of Rectal Cancer with Synchronous Hepatic and Pulmonary Metastases with Individualized Therapy

结直肠癌肝转移患者自然生存时间为6～12个月,同时伴有肺转移的生存时间更短。单纯化疗后可延长至12～24个月。对于结直肠癌肝转移患者,绝大多数死于肝脏的病灶。结直肠癌肝转移行肝切除术者,5年生存率大约40%。根治性手术切除是治疗结直肠癌肝转移的最佳方法,放化疗亦具有重要价值。现介绍1例天津医科大学附属肿瘤医院经肝胆肿瘤科、肺部肿瘤科治疗的直肠癌术后同时性肝肺转移的病例,该患者经多学科的协作诊疗后效果较佳,报道该病例诊治经验以促进结直肠癌诊疗技术和经验的全面融合,推动多学科间的交流与合作。

Objective： The overall survival time of colorectal cancer patients with hepatic metastasis is 6 months to 12 months, and is shorter in patients with synchronous pulmonary metastasis. Regular chemotherapy prolongs patient survival for up to 12 months to 24 months. The majority of cotorectal cancer patients with liver metastasis die of hepatic lesions. The postoperative 5-year survival rate is approximately 40 %. Radical resection is the optimal treatment for colorectal cancer case with hepatic metastasis. Radiotherapy and chemotherapy are needed for treating this disease. The current study presents a post-operative rectal cancer patient with synchronous hepatic and pulmonary metastases, who underwent a multidisciplinary team （ MDT ） therapy in this hospital. The multimodal treat- ment achieved a favorable curative effect for the patient. MDT treatment promotes comprehensive integration of colorectal cancer diagnosis and treatment strategies and experience, and it could enhance interdisciplinary communication and cooperation among medical colleagues in the same fields.