低温等离子消融术治疗慢性鼻炎的疗效观察

Effect of low-temperature plasma radiofrequency ablation on chronic rhinitis

目的探讨低温等离子消融术治疗对以鼻塞为主要症状的成人慢性鼻炎患者主观症状、鼻腔黏膜纤毛清除功能及鼻阻力的影响。方法将门诊诊断为慢性鼻炎的62例患者分为治疗组和对照组,分别行低温等离子消融术治疗和等渗盐水鼻腔冲洗加鼻内类固醇激素治疗,治疗1年后检测患者主观症状、黏膜纤毛清除时间及鼻阻力变化,并与治疗前进行对比分析。结果治疗前患者平均糖精清除时间为17.42 min;治疗后治疗组患者平均糖精清除时间为17.26 min,对照组患者平均糖精清除时间为16.82 min,治疗组与对照组比较差异无统计学意义(P>0.05)。鼻阻力检测示,治疗组鼻阻力明显减小,且其减小程度与对照组比较差异具有统计学意义(P<0.01)。与治疗前相比,视觉模拟量表(VAS)评分示治疗组患者鼻塞症状明显改善(P<0.05),且改善程度优于对照组。结论低温等离子下鼻甲消融术治疗对慢性鼻炎患者鼻腔黏膜清除功能影响不明显,但可显著减小鼻阻力,且对患者主观症状改善显著。

Objective To determine the effect of low-temperature plasma radiofrequency ablation （LTPRA） for the treatment of chronic rhinitis. Methods 62 patients with chronic rhinitis were divided randomly into two groups, the treatment group undertaken LTP IRA of inferior turbinate, and the control group received saline nasal irrigation and intranasal corticosteroid treatment. The subjective symptoms, mucociliary clearance time and nasal resistance were assessed before and one year after treatment respectively. Results Before treatment, the total average mueociliary clearance time was 17.42 min. One year Mte3r treatment, the mucociliary clearance time of LTPRA group was 1 7 . 2 6 rain , which was insignificantly different from that of the control group （ 1 6 . 8 2 rain ） （ P 〉 0.05 ）. Compared to the parameters before treatment, the nasal resistance was significantly decreased in LTPRA group （ P 〈 0.01 ） , and visual analogue scale （ VAS ） evaluation showed LTPRA treatment significantly improved subjective symptoms （ P 〈 0.01 ）. The differences in decrease of nasal resistance and improvement of subjective symptoms between the LTPRA group and the cotrol group were statistically significant （ both P 〈 0.01 ）. Conclusion Low-temperature plasma radiofrequency ablation can significantly decrease nasal resistance and improve subjective symptoms, and therefore is safe and effective for chronic rhinitis.