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靶向释放智能纳米载体的研究进展 被引量：2

Research Progress in Intelligent Nano-Carriers for Targeted Delivery
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摘要 随着材料科学的进步,智能纳米载体在药物和基因靶向治疗方面取得了巨大的研究进展。智能纳米载体被化学信号、温度、pH等"触发器"激发后,能在特定部位响应性地释放药物或基因。该文从智能纳米载体的定义,不同类型靶向释放的智能纳米载体在药物和基因中的研究进展,靶向释放的智能纳米载体的不足及发展前景等方面进行综述。 With the advances in material science, intelligent nano-carriers for targeted drug and gene delivery have made tremendous progress. In response to stimuli including chemical molecules, temperature and pH, drugs and genes could be released from intelligent nano- carriers in targeted tissues and organs. This review contains three parts of intelligent nano- carriers, definition, research advance on different types of targeted delivery intelligent nano-carriers in drug and gene, and disadvantage and development prospect of intelli- gent nano-carriers for targeted delivery.
作者 顾君彤 徐维平 陆杨 徐婷娟 黄向华 张勇强
机构地区 安徽中医学院研究生部 安徽省立医院 中国科学技术大学
出处 《中国药业》 CAS 2012年第21期1-3,共3页 China Pharmaceuticals
基金 安徽省学术和技术带头人及后备人选学术科研经费资助 项目编号:11040606M193
关键词 智能纳米载体 靶向释放 传输 药物 基因 intelligent nano - carriers targeted release delivery drug gene
分类号 R944.9 [医药卫生—药剂学]
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参考文献25

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共引文献5

同被引文献73

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引证文献2

二级引证文献8

中国药业
2012年 第21期

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