高支化f-CTBN/PEG聚氨酯的合成与降解性能研究

Preparation and Degradation of these Highly-branched f-CTBN /PEG Polyurethanes

采用逐步聚合的方法,以功能化丁腈橡胶(f-CTBN)与不同相对分子质量(Mn)聚乙二醇(PEG)共聚合得到一系列高支化嵌段聚氨酯(f-CTBN/PEG)高分子材料。通过对材料溶胀性,模拟生物环境降解,以FT-IR对基团变化分析和ESEM形貌观察,以及力学性能的测试。结果表明:材料的降解速率随时间延长呈减慢趋势,且随PEG含量的增大材料降解越快;拉伸强度(超过18MPa)和杨氏模量(超过40MPa)相对较高。有望根据需求来调节f-CTBN/PEG的比例大小,从而用于医用防护材料的生产。

A series of novel polyurethane （PU） scaffolds were designed and prepared on the basis of hyper branched earboxyl-terminated poly （butadiene-co-acrylonitrile） （f-CTBN）, poly （ ethylene glycol） （PEG） and diisocyanate curing agents by a coupling or step-by-step synthetieal method. The biodegradation mechanisms at different time periods of hydrolysis were characterized by Fr-IR and ESEM. The effect of PEG volume fraction on tensile and extend, degradation properties of materials were discussed respectively. Simultaneously, the hydrophilicity was tested with the swelling. The experimental results indicated that the mass loss of samples is enhanced with increasing PEG concentrations and its molecular weight （mol. wt. or Mn）, and degradation residues exhibit increasing porosity with time period of hydrolysis. The tensile strength （more than 18 MICa） and Young＇ s modulus （more than 40MPa） showed that the highly crosslinked architecture offers the high tensile strength. Therefore, these PU materials will have huge application potentials in the biomedical field, especially in the medical care products.