肝硬化并发全血细胞减少患者的骨髓象分析及临床意义

Analysis of Bone Marrow in 73 Patients with Cirrhosis and Pancytopenia

目的观察分析73例病毒性肝炎引发肝硬化并发全血细胞减少患者的骨髓象变化情况并探讨其临床意义。方法利用瑞氏染色法（Wright’Sstaining）对73例肝硬化并发全血细胞减少患者的骨髓进行染色，在光学显微镜下进行骨髓有核细胞增生分级及分类计数。结果在73例病毒性肝炎后肝硬化并发全血细胞减少患者的骨髓象中，骨髓增生极度活跃的5例，增生明显活跃的16例，增生活跃的44例，增生减低的8例；骨髓细胞分类主要表现为红细胞系的增生、粒细胞系和巨核细胞系的成熟障碍。结论骨髓象分析是造血系统疾病的重要检测指标之一，病毒性肝炎所引发的肝硬化并发全血细胞减少患者的骨髓细胞学检查结果对于排除患者造血系统疾病及进一步临床诊疗具有极为重要的指导价值。

Objective To analysis the result of bone marrow in 73 patients with cirrhosis and pancytopenia,investigate the characteristics and the value of laboratory indicators for the diagnosis of the disease. Methods The nucleated cells in bone marrow samples were examined with Wright^s staining. The samples were collected from the patients of 73 patients with cirrhosis and paneytopenia. The baperplastic degree of nucleated cells of bone marrow was observed under light microscope. Results The bone marrow proliferative activities were different among 73 patients with cirrhosis and pancytopenia. There were extremely active in 5 case,remarking active in 16 cases,active in 44 cases and depressed active in 8 cases respectively. Conclusion The analysis of Bone marrow is one of the important indicators in diseases of hematopoietic system,the results of patients with cirrhosis and paneytopenia should be the important indicators to exclusive hematopoietic system disease and clinical diagnosis and treatment.