口腔颌面部恶性肿瘤免疫治疗的护理

The nursing care of immune cell therapy on malignant tumors in oral and maxillofacial region

目的探讨免疫治疗口腔颌面部恶性肿瘤患者的护理操作原则。方法对中山大学附属口腔医院收治的63例免疫治疗口腔颌面部恶性肿瘤患者进行回顾性分析,评价其免疫治疗的护理特点。结果 2009年1月至2011年12月,63例患者进行免疫治疗共413例次。其中静脉回输405例次、动脉灌注8例次,同期进行瘤体注射65例次。出现低度发热29例、中度发热11例、高度发热5例、短暂性寒颤7例、恶心呕吐11例、轻度皮疹3例,经积极治疗和护理后好转,未出现严重不良反应。全部患者均顺利安全完成免疫治疗。结论在临床医疗护理中应根据免疫治疗方案给予患者个性化的对症护理,加强患者的心理指导。口腔颌面部恶性肿瘤多途径免疫治疗是安全可靠的方法。

Objective To investigate principles for the nursing care in immune cell therapy on oral cancer. Methods The clinical data of 63 cases with malignant tumors in oral and maxillofaeial region were analyzed retrospectively to evaluate the nursing d, haracteristics of these patients during immune cell therapy. Results From January 2009 to December 2011, 63 patients were treated 413 times concluded with intravenous injection 405, arterial infusion 8 and intra-tumor injection 65 times. There were 45 cases having fevers, 7 cases＇ having vomiting, 7 cases having shivers and 3 cases having rash out of the 413 times of treatment. All patients had successfully completed immune cell therapy smoothly. Conclusions Clinical medical care programmes should based on its treatment in patients with symptomatic of personalized care, strengthen the psychological guidance for patients. Immune cell therapy provides a realistic new option in the field of oral cancer immunotherapy.