异位妊娠血HCG与孕酮变化的关系

Change relationships between HCG and progesterone level in blood in ectopic pregnancy

目的探讨HCG与孕酮在异位妊娠及正常妊娠组中不同孕周的变化情况,并以此为依据评价此两种指标。方法选择39例异位妊娠患者和48例正常妊娠妇女,再根据孕期不同将其分为三个亚组,检测各组患者血清中HCG和孕酮的含量。结果以正常妊娠组做对比,在各孕期异位妊娠组血清孕酮都较低(P<0.05),HCG水平在孕5周和孕6周时较低(P<0.05);两组中HCG水平随孕期增加而上升(P<0.05),而孕酮水平并未发生明显变化(P>0.05)。结论相比血清中HCG水平,孕酮含量的检测可更早地诊断异位妊娠,同时诊断效果更高。

Objective To investigate the change in HCG and progesterone level of ectopic pregnancy group and normal pregnancy group in blood in different gestational weeks,and to evaluate these two indices. Methods 39 cases of ectopic pregnancy and 48 cases of normal pregnancy were selected, and divided into three subgroups. The level of HCG and pro- gesterone in blood were detected. Results Compared with the normal pregnancy group,in ectopic pregnancy group, proges- terone level was lower in each gestational weeks （P 〈 0.05）, and HCG was at the lower level in the 5th and 6th gestational weeks （P 〈 0.05）. I-ICG level was increased, while progesterone level showed no changes as the gestational week increased in both of these groups. Conclusion Compared with HCG, the detection of progesterone level could help clinicians to di- agnose ectopic pregnancy more early, and it has better effect on diagnosis.