超声造影评价颈动脉粥样硬化价值

Value of contrast-enhanced ultrasound to the evaluation of carotid atherosclerosis

目的探讨超声造影检查在颈动脉粥样硬化疾病中的应用价值。方法 15例颈动脉粥样硬化患者采用超声造影检查,观察造影前、后颈动脉管腔显示情况、斑块数量、形态特征、评估狭窄程度,并与数字减影血管显像或MRA结果进行对照。结果超声造影后检出斑块个数(43个)与造影前(32个)比较差异有统计学意义(P<0.05);以数字减影血管显像或MRA结果为标准,造影后诊断颈动脉狭窄程度的敏感性(100.0%)、特异性(98.3%)及准确率(97.6%)均明显高于造影前(分别为95.2%,89.2%,90.4%)(P<0.05)。结论超声造影是诊断颈动脉疾病的有效方法之一。

Objective To approach the value of contrast-enhanced ultrasound to the evaluation of carotid atherosclerosis. Methods Fifteen patients with carotid atherosclerosis underwent contrast-enhanced ultrasound. Before and after injection of contrast agent, the carotid lumen was observed, the amount and the character of the plaques were detected, and the stenosis degree was measured and compared with DSA or MRA. Results There was a significant difference in the amount of detected plaques （32 vs 43） between before and after injecting contrast agent （P〈0.05）. The sensitivity, specificity and accuracy of the stenosis degree were significantly higher after injecting contrast agent on the basis of DSA and MRA results （100. 0%, 98. 3%, 97. 6%） as eompared with those before injecting contrast agent （95.2 %,89. 2%,90. 4 %） （P 〈 0. 05）. Conclusion Contrast-enhanced ultrasound is one of the useful methods for diagnosis of carotid atherosclerosis.