脂肪乳预防急性有机磷农药中毒所致外周型呼吸肌麻痹的临床研究

Fat Emulsion to Prevent Acute Organophorus Pesticide Poisoning Caused by Periphereal Type Breathing Machine Paralysis of Clincal Research

目的探讨预防有机磷农药中毒所致的RMP的治疗方法。方法随机将247例中重度有机磷农药中毒患者分为两组,A组为对照组121例,常规给予洗胃解毒对症支持治疗;B组126例,除常规治疗外每日加用10%脂肪乳500 ml静滴一次,给予5 d。结果 A组患者RMP发生4例,B组患者RMP发生1例,A组与B组患者RMP的发生率有显著差异(P<0.01)。结论脂肪乳在一定程度上可预防有机磷农药中毒所致RMP的发生。

Objective To probe into the treatment in how to prevent the RMP caused by AOPP. Methods Divide 247 mid- dling and severe AOPP cases into 2 group. Group A, the comparison, 121cases, giving routine treatment of stomach watching and de- toxification. Group B, 126 cases, besides routine treatment, add 500ml 10% intralipid vein transfusion once a day, giving 5 days. Re- sults Group A, RMP coourrence 4 cases, while group B none. The rate of RMP occurrence between group A and group B having obvious different （P〈0.01）.Conclusion Intralipid can effective prevent RMP caused by AOPP.