抑癌基因的活性检测在人体衰老评估中的意义

The significance of activity detection for tumor suppressor gene in the assessment of human aging

细胞衰老是机体衰老的基础,是人类老年相关疾病发生的前提。研究表明,衰老与肿瘤发生有着密切的关系,抑癌基因可能是与肿瘤和衰老调节相关联的关键基因,其表达水平的高低与细胞增殖调控、细胞分化、肿瘤发生相关联,因而对与衰老相关的抑癌基因进行活性检测将有助于对老年病和肿瘤等疾病的发生、发展有更好的了解,为癌症的防治和对抗衰老提供广阔的前景。

Cell aging is the foundation of human body aging,is the premise of human aging-related diseases.Research shows that tumorigenesis associated with aging,tumor suppressor gene is the key gene contact with the tumor and aging,the cell proliferation,tumorigenesis and cell differentiation connect with its expression level.So aging-related tumor suppressor gene activity detection will contribute to the occurrence of the senile disease and tumor,provide a prospects for tumor prevention and anti-aging.