加温湿化氧疗在重型颅脑损伤患者中的应用研究

The application of heated humidification oxygen therapy during weaning from ventilation in patients with severe traumatic brain injury

目的探讨重型颅脑损伤患者脱机后使用持续加温湿化氧疗的效果。方法将80例重型颅脑损伤随机分为观察组和对照组,各40例,观察组采用新型氧疗机进行加温湿化给氧,对照组采用传统人工鼻湿化给氧。结果观察组患者呼吸频率、痰液黏稠度、二氧化碳分压及肺部感染率均显著低于对照组(P<0.01)。结论持续加温湿化氧疗对重型颅脑损伤患者的湿化效果满意,能有效降低肺部感染率。

Objective To evaluate the effectiveness of continues heated humidification oxygen therapy during weaning from ventilation in after ventilator withdrawal. Methods 50 eases of severe traumatic brain in- jury patients were divided into experimental and control groups, each 25 cases. The experimental group was given airway humidification and oxygen therapy with production of oxygen therapy machine （ Fisher ＆ Paykel Health- care Corporation, New Zealand）. Control group used traditional artificial nasal airway humidification of oxygen. Results The airway environmental indicators like respiratory rate, sputum viscosity, partial pressure of carbon dioxide were significantly lower than which in the control group, with a significant differences （ P 〈 0.01 ）. The occurrence of pulmonary infection in the experimental group was lower than which in the control group （ P 〈 0.01）. Conclusion The oxygen therapy machine is better than traditional artificial nose of humidification and maintain toward airway environment in severe traumatic brain injury patients, and can reduce pulmonary infec- tion rate in a certain degree.