1,3,5-三甲氧基苯与苯甲酰氯的反应研究

Study on the reaction of 1,3,5-trimethoxybenzene with benzoyl chloride

在无水三氯化铝催化下 ,1,3 ,5 三甲氧基苯与苯甲酰氯可进行酰化去甲基再酰化三个连续步骤 ,反应可生成三种产物 :2 ,4 ,6 三甲氧基二苯甲酮、2 羟基 4 ,6 二甲氧基二苯甲酮和 3 苯甲酰基 2 羟基 4 ,6 二甲氧基二苯甲酮三种化合物 .初步讨论了反应机理 .新化合物的结构都经过元素分析、1

The reaction of 1,3,5 trimethoxybenzene with benzoyl chloride in the presence of catalyst included three proceeding steps: F C reaction, demethylation and F C reaction again,obtaining three kinds of compounds as 2,4,6 trimethoxy benzophenone, 2 hydroxyl 4,6 dimethoxy benzophenone and 3 bnezoyl 2 hydroxyl 4,6 dimethoxy benzophenone. The reaction mechanism was discussed. The structures of new compounds were identified by elemental analysis, 1H NMR and IR.