尿微量白蛋白与高血压病关系浅析

Primary Analysis of the Relation Between Microscale Albuminuria and Hypertension

目的了解尿微量白蛋白(MAU)与高血压肾病的关系。方法采用免疫比浊法检测168例高血压患者与125例健康体检者的MAU情况,对两组间及高血压患者在不同性别、不同病程的MAU阳性率进行比较。结果高血压病组MAU阳性率高于健康组,差异有统计学意义(p<0.01);5-10年病程组MAU阳性率低于10年及以上病程组,差异有统计学意义(p<0.05)。结论定期对高血压患者进行MAU检测有助于早期监测高血压肾病的进展情况,同时有助于临床医师对病人病情的判断和确定合理的治疗方案。

Objective To have a knowledge about the relation between microscale albuminuria（MAU） and hypertensive nephropathy.Method The MAUs of 168 patients with hypertension and 125 healthy people were detected with immunonephelometry,and the MAU positive rates of patients with different gender and at different clinical phases between the two groups and in the group with hypertension were compared.Results The MAU positive rate in the group with hypertension was higher than the healthy group,and the differences were statistically significant（p0.01）;the MAU positive rate in the group with a clinical phase between 5-10 years was lower than the group with a clinical phase over 10 years,and the differences were statistically significant（p0.05）.Conclusion Regular detection of MAU for patients with hypertension is helpful to early monitor the advance of hypertension and for clinicians to judge patients＇ condition so as to make proper treatment scheme.