育龄妇女宫颈病变的筛检研究

Research of Screening for Cervical Lesion Among Women of Childbearing Age

目的探讨育龄妇女宫颈不良病变的特征,评价女性宫颈病变的发展趋势,探索有效的预防措施。方法收集本院妇科门诊2009-2011年TCT筛检人群资料,共5 860例女性合格宫颈细胞标本进行TCT检查,对TCT阳性对象再进行活检病理诊断。结果 5 860例标本中共筛检出138例宫颈细胞异常标本,其中ASC/AGC 120例,检出率2.05%;LSIL 8例,检出率0.14%;HSIL 6例,检出率0.10%;SCC/AC 4例,检出率0.07%;20岁以下年龄组2例,20岁至30岁组37例。病理活检有131例确诊,占TCT阳性者的94.93%,其中CINⅠ47例,检出率为0.8%;CINⅡ49例,检出率0.84%;CINⅢ38例,检出率0.65%;鳞癌/腺癌4例,检出率为0.07%。结论宫颈病变在育龄妇女中有较高的检出率,并出现年轻化趋势,TCT筛查是及早发现癌前病变及防治宫颈癌的关键。

Objective To probe into the characteristics of the cervical malignant lesions among women of childbearing age and evaluate the development trend of cervical lesions among the female so as to explore effective preventive measures.Method Data of patients who had TCT screening in the gynecology outpatient department of our hospital from 2009 to 2011 were collected.The qualified samples of cervical cell from a total of 5 860 females were screened with TCT and pathological diagnosis by biopsy was made for the positive results.Results A total of 138 cervical cell samples were screened as abnormal from the 5 860 samples,among which there were 120 cases of ASC/AGC with a detection rate of 2.05%;8 cases of LSIL with a detection rate of 0.14%;6 cases of HSIL with a detection rate of 0.10%;4 cases of SCC/AC with a detection rate of 0.07%;there were 2 cases in the group under 20 years old and 37 cases in the group between 20 and 30 years old.The pathologic biopsy made a definite diagnosis of 131 cases,which accounted for 94.93% of the TCT positives,including 47 cases of CINⅠwith a detection rate of 0.8%;49 cases of CINⅡwith a detection rate of 0.84%;38 cases of CIN Ⅲ with a detection rate of 0.65% as well as 4 cases of squamous carcinoma /adenocarcinoma with a detection rate of 0.07%.Conclusion The detection rate of the cervical lesions is relatively high among women of childbearing age,which presents a youth-oriented tendency,and the TCT screening is crucial to find out precancerous lesions and prevent and cure the cervical carcinoma.