1540例大学生痤疮临床分析

Clinical Analysis of Acne in 1540 University Students

目的了解大学生痤疮的发生类型及严重程度,寻找在高校医院条件下治疗痤疮的有效方法。方法对在武汉大学医院就诊的1 540例大学生痤疮患者按照痤疮的6个级别进行临床分型,按4个级别进行临床分度,对临床分级和严重程度进行分析。试验组132例用替硝唑静脉治疗,对照组98例用替硝唑、罗红霉素口服治疗,进行疗效比较。结果大学生痤疮类型排在前3位的是丘疹、脓疱型和结节型,其比例分别为44.4%、17.4%和16.7%,囊肿、萎缩型和聚合型较少。痤疮的严重程度I°、Ⅱ°、Ⅲ°、Ⅳ°分别为76.1%、17.8%、4.3%和1.8%。试验组有效率为89.4%,高于对照组的55.1%,差异有统计学意义(χ2=6.305,p<0.01)。结论大学生痤疮多数为丘疹、脓疱和结节型,严重度以I°、Ⅱ°为主。治疗以静滴替硝唑疗效优于口服替硝唑、罗红霉素。

Objective To have knowledge about the incidence type and severity of acne in 1 540 university students so as to look for an effective way to treat the acne under conditions of the university hospital.Method 1 540 university students with acne treated in our hospital were classified clinically according to six levels of the acne and they were graded clinically according to four levels of the acne,and the clinical grade and severity were analyzed.132 cases in the experimental group were treated with intravenous tinidazole and 98 cases in the control group were treated with peroral tinidazole and roxithromycin,and the therapeutic effects were compared.Results Acne of university students ranking the top three was papules,pustules,nodules with a respective percentage of 44.4%、17.4% and 16.7% while cysts,acne atrophica and acne conglobata seldom occurred.The severity of acne was I°、Ⅱ°、 Ⅲ° and Ⅳ°accounting for 76.1%、17.8%、4.3% and 1.8% respectively.Effective rate of the experimental group was 89.4%,which was higher than 55.1% of the control group,and the differences were statistically significant（χ2=6.305,p0.01）.Conclusion The most acne that university students suffer from is papules,pustules,nodules and the severity is mainly I° and Ⅱ°.The therapeutic effect of tinidazole by intravenous drip infusion is better than that of peroral tinidazole in treating acne.