摘要
目的探讨急诊室给予替罗非班对ST段抬高型急性心肌梗死(STEMI)患者梗死相关动脉(IRA)再通和经皮冠状动脉介入(PCI)术后即刻心肌灌注的影响。方法治疗组47例患者PCI术前在急诊室给予替罗非班,对照组50例患者在PCI术中给予替罗非班,观察两组急诊造影中IRA再通率、PCI术后即刻靶血管TIMI血流分级及不良反应发生率。结果急诊造影时IRA再通率(38.29%)显著高于对照组(20.00%),两组差异有统计学意义(P<0.05)。急诊造影时TIMI血流Ⅲ级患者治疗组(34.04%)显著高于对照组(10.00%),两组比较差异有统计学意义(P<0.05)。术后即刻靶血管TIMI血流Ⅲ级患者治疗组(93.62%)显著高于对照组(76.00%),两组比较差异有统计学意义(P<0.05)。结论 STEAMI患者PCI术前急诊室即予替罗非班治疗能提高急诊造影时IRA再通率,改善术后即刻心肌灌注,且安全性好。
Objective To explore the effect of treatment with tirofiban in emergency room on infarction ralated artery（IRA） and TIMI blood flow in patients suffered ST elevation myocardial infarction（STEMI）.Methods A total of 97 patients were included in the study,47 of them accepted the treatment of tirofiban in emergency room were divided into the observed group,others were divided into the control group.The difference of the recanalization rate of IRA when emergency angiography,the immediate target vessel TIMI flow classification and incidence of adverse reaction were compared between the two groups.Results The recanalization rate of IRA when emergency angiography was significantly higher in the observed group（38.29%） than that of the control group（P0.05）.The proportion of class III of arget vessel TIMI flow when emergency angiography was significantly higher in the observed group（34.04%）than that of the control group（10.00%）（P0.05）.The proportion of class III of the immediate target vessel TIMI flow was significantly higher in the observed group（93.62%）than that of the control group（76.00%）（P0.05）.Conclusions Treatment with tirofiban in emergency room could improve the recanalization rate of IRA and TIMI blood flow in patients suffered STEMI.
出处
《心脑血管病防治》
2012年第5期368-370,共3页
CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
