高尿酸血症与冠心病关系的研究

Research of relationship of hyperuricemia and coronary heart disease

目的探讨高尿酸血症与冠心病的关系。方法选择临床确诊的冠心病患者43例及同期健康查体者50例,分别检测两组对象的血尿酸、血脂以及血糖。结果冠心病患者的血尿酸、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)与健康人相比较,差异具有统计学意义(P<0.01);2、3支冠脉病变与单支病变者相比较,差异具有统计学意义。结论冠心病患者的血尿酸明显升高,高尿酸血症很可能是冠心病发生的另一大危险因素。

Objective To explore the relationship of hyperuricemia and coronary heart disease.Methods Forty-three cases clinically diagnosed with coronary heart disease and the same period 50 cases of healthy people were detected the serum uric acid,lipids and blood sugar.Results Serum uric acid,high-density lipoprotein （HDL） and low-density lipoprotein （LDL） of coronary heart disease patients compared with healthy people,the difference was statistically significant （P 0.01）.The 2,3 branch coronary artery lesions compared to single artery lesion,the difference was statistically significant.Conclusion The serum uric acid of coronary heart disease patients is significantly increased;hyperuricemia is likely another major risk factor of coronary heart disease.