多潘立酮联合氟哌噻吨美利曲辛片治疗原发性胆汁反流性胃炎的疗效观察

Clinical observation on Domperidone combined with Flupenthixol Melitracen tablets in treatment of primary bile reflux gastritis

目的观察多潘立酮联合氟哌噻吨美利曲辛片治疗原发性胆汁反流性胃炎(PBRG)患者的疗效。方法将78例PBRG患者随机分为两组,多潘立酮联合氟哌噻吨美利曲辛片组(观察组)和单用多潘立酮组(对照组),疗程均为4周,观察药物疗效。结果治疗后,观察组的总有效率(82.5%)显著高于对照组(55.3%)。结论在PBRG的治疗过程中,适当采用氟哌噻吨美利曲辛与促动力药联用,可以提高治愈率,对于常规内科治疗效果不佳的PBRG患者,可以考虑联合应用氟哌噻吨美利曲辛。

Objective To observe the effect of Domperidone combined with Flupenthixol Melitracen tablets in treatment of patients with primary bile reflux gastritis （PBRG）.Methods Seventy-eight cases of patients with PBRG were randomly divided into Domperidone combined with Flupenthixol Melitracen tablets group （observation group） and single domperidone group （control group）,the course of treatment were all 4 weeks,and the curative effects of medicine were observed.Results After treatment,the total efficiency of observation group （82.5%） was significantly higher than that of control group （55.3%）.Conclusion In the therapeutic process of PBRG,appropriate using Flupenthixol Melitracen combined with prokinetic drugs can improve cure rate.For PBRG patients with poor treatment outcomes of conventional medical treatment can considere the therapy of conventional medical treatment combined use with Flupenthixol Melitracen.