不同季节和献血次数对献血者ALT的影响

Different season and blood donation times to ALT unqualified influence

目的:调查分析不同季节和献血次数对丙氨酸氨基转移酶(ALT)的影响,探讨ALT阳性导致血液报废的应对策略,以利于对献血者的征募、初筛和固定献血队伍的建设。方法:对邯郸市2009年3月～2010年2月18～55岁20 847名献血者ALT、HBsAg、抗-HCV、抗-HI V、抗-TP5项检测结果行Epi dat a3.0双录入,导入SPSS13.0,将健康献血者根据献血日期按气候季节分为4个组,根据献血次数分为首次、再次、多次献血3个组,用检验、分割检验、趋势检验分析不同季节和献血次数对ALT不合格的影响。结果:各季节ALT不合格率的比较,χ2=349.670,P<0.001,差异有统计学意义,采用分割进行两两比较:除夏季和冬季无差异(χ2=3.155,P=0.076)外,其余各组间均有差异(P<0.001),秋季最高,春季最低。不同献血次数ALT不合格率差异有统计学意义(P<0.001),经趋势检验,随着献血次数的增加,ALT不合格率有增加的趋势(χ2=35.515,P<0.001)。结论:不同献血季节和献血次数的不同对ALT的不合格都有影响,在献血者招募时应注重在ALT较高季节(秋季)和对多次献血者加强献血知识的宣传。

Objective Investigation and analysis Different season and blood donation times to ALT unqualified influence.Explore the blood ALT positive leading to scrap strategy,for the donors to recruit,and early screening,and the building for fixed blood donation team.Methods In March of 2009～2010 February in Handan,18 to 55 years old 20847 donors' five test results(ALT、HBsAg、Anti-HCV、Anti-HIV、Anti-TP) do Epidata3.0 double entry,import SPSS 13.0.Divided health donors into four groups according to donation climate season,To divided into three groups according to donation frequency:the first,again,and many times.Using the chi-square test,post hoc multiple chi-square,and chi-square tendency test to analysis Different season and blood donation times to ALT unqualified influence.Results Eachseason ALT rejects comparison:χ2=349.670,P<0.001,there has statistical difference between groups.Post hoc multiple comparisons using chi-square segmentation,there have no statistical difference between summer and winter(χ2=3.155,P=0.076).The other seasons all have difference between(P<0.001).Autumn was most important factors in rising ALT unqualified,and summer was lowest.There were statistically significant between different blood donation times in ALT unqualified(P<0.001).Using trend of the chi-square test,with increasing of donation times ALT unqualified percenttrend to increase(χ2=35.515,P <0.001).Conclusion Blood donation season and times all have influence to ALT unqualified.When in blood donors recruitment should pay attention and strengthen the propaganda of blood donation knowledge in ALT unqualified high season(autumn) and blood donation many times.