男性乳腺癌36例诊治分析

Diagnostic and therapeutic analysis to 36 cases of male breast cancer

目的 :探讨男性乳腺癌的特点及影响预后的因素。方法 :总结 180 0例乳腺癌中 36例男性乳腺癌的发病率、病因、诊断、病理、治疗及预后的差异。结果 :本组男性乳腺癌发病率为 1.2 %。临床分期Ⅰ期 6例 (16 .7% ) ,Ⅱ期 5例 (13.9% ) ,Ⅲ期 2 1例 (58 3% ) ,Ⅳ期 4例 (11 1% )。 32例手术治疗 ,腋窝淋巴结转移率为 6 8 8%。淋巴结转移程度为 16 4 %。病理类型以浸润性非特殊型癌为主。 5年生存率为 76 5% ,10年生存率为 30 0 % ,明显低于女性。结论 :男性乳腺癌发病率低 ,临床分期较晚。癌组织细胞分化较低 ,预后较差 ,易早期转移。治疗上应以根治术为主的综合治疗。

Objective:To investigate the characteristics and the prognosis influencing factors of male breast cancer.Methods:To conclude differences of the incidence, etiology, diagnosis, pathology, treatment and prognosis of 36 male patients.Results:The incidence of breast cancer of this group was 1.2% ,6 of those ( 16.7% ) were stage I, 5 were stage Ⅱ(13.9%),21 were stage Ⅲ(58.3%),4 were stage Ⅳ(11.1%),and 32 of those were treated by operation,68.8% of those had axillary lymph nodes metastasis, the metastatic of lymph nodes is 16.4%. The major pathological type was infiltrative non specific cancer. The five year survival rate was 76.5%, ten year survival rate was 30.0%,which were lower than those of female. Conclusions:Male breast cancer has lower incidence, later clinical stage, lower differentiation and poor prognosis, and early metastasis.Early diagnosis and treatment is important, frozen section during operation and radical resection are necessary for the subareolar mass in elder men.