青海地区泌尿系结石成分分析及防治

Qinghai urinary calculi in composition analysis and prevention

目的:研究青海地区581例泌尿系结石化学构成,为临床预防、治疗提供依据。方法:化学反应测定581例泌尿系结石标本,研究其成分,并结合临床资料进行比较。结果:在581例尿石中混合结石占70.56%(410/581),其中草酸盐结石59.89%,磷酸盐结石34.59%,碳酸盐结石24.61%,尿酸结石26.33%;单纯结石17.42%。上尿路结石473例,下尿路结石108例,上、下尿路结石之比为4.36:1,肾、输尿管结石主要以草酸钙和磷酸钙混合结石及单纯草酸钙结石为主,膀胱结石主要以尿酸结石为主,尿路结石部位和化学成份构成密切相关,肾、膀胱结石与其化学成份构成经统计学检验差异有显著性(P<0.05),提示上、下尿路结石的发病机理不同。结论:结石成分分析对于了解结石成因、预防结石形成和复发具有重要的意义。

Objective To study the 581 cases of qinghai region urinary calculi chemical composition, for clinical prevention, treatment, provides the basis. Methods 581 cases of chemical reaction determination of urinary calculi specimens, and study the composition, and combined with clinical data are compared. Results Among 581 cases in urine mixed stones accounted for 70.56%（410/581）, of which 59.89% salt oxalate stone, phosphate stone 34.59%, 24.61% carbonate stone, stone uric acid 26.33%; Simple stone 17.42%. Urinary calculi in 473 cases, urinary calculi under 108 cases, on under the ratio of urinary calculus 4.36：1, kidney, ureter stone mainly calcium oxalate stone and calcium phosphate and mixed pure calcium oxalate stone is given priority to, bladder calculi mainly uric acid as stone, urinary calculus parts and chemical composition constitute a closely related, the kidney, bladder calculus and its chemical composition form after statistics inspection （P〈0.05）, hintunder the pathogenesis of urinary calculus is different. Conclusion stone composition analysis to understand the stone cause, prevention stone formation and recurrence is of great significance.