姑息性切除中晚期肝癌43例分析

ANALYSES OF PALLIATIVE RESECTION IN 43 CASES WITH ADVANCED HEPATOCELLULAR CARCINOMA

目的 评价癌肿姑息切除在中晚期肝癌治疗中的作用。方法 把我院肝胆外科于 1996年 3月至 1999年 6月收治的 86例 (术中证实不能行根治性切除者 )中晚期肝癌患者随机分成两组 ,治疗组行癌肿大部分切除 +肝动脉置管埋泵化疗等综合治疗 ,对照组剖腹行肝动脉置管埋泵化疗等综合治疗。结果 治疗组及对照组的 AFP下降率和半年、1年、3年的生存率分别为 6 1.1%(2 2 / 36 )、88.4% (38/ 43)、5 9.4% (19/ 32 )、44 .4% (8/ 18) ,31.5 % (12 / 38)、6 7.4% (2 9/ 43)、33.3% (12 / 36 )、11.8% (2 / 17) ,两者比较P<0 .0 5 ,差异有显著性。

Objective To evaluate the effect of palliative resection in advanced hepatocellalar carcinoma.Methods From March 1996 to June 1999,86 patients with advanced hepatocellular carcinoma were randomly divided into two groups in our hospital.In the group of treatment,the patients were treated with palliative resection of liver cancer and implanted Drug Delivery Systerm(IDDS).In the control group,patients were performed IDDS.Results In the two groups,The rate of decline of AFP and survival rates in half year,one year and three years after operation were 61.1%(22/36)、88.4%(38/43)、59.4%(19/32)、44.4%(8/18),31.5%(12/38)、67.4%(29/43)、33.3%(12/36) and 11.8%(2/17) respectively (P<0.05).Conclusion Palliative resection of liver cancer was able to incerease the life quality of patients with advanced hepatocellular carcinoma.