新生儿高胆红素血症与人巨细胞病毒感染的关系

THE STUDY OF HUMAN CYTOMEGALOVIRUS INFECTION AMONG NEONATE WITH HYPERBILIRUBINEMIA.

为了解高胆红素血症 (简称高胆 )新生儿中人巨细胞病毒(HCMV)感染状况。方法 :用聚合酶链反应 (PCR)技术对 12 0例 12～ 2 8天高胆新生儿的血、尿进行 HCMV- DNA序列测定。结果 :因出生有窒息史、感染致高胆的新生儿中 HCMV- DNA阳性率分别为 3.1% (1/ 32 ) ,8.1% (3/ 37)。因高胆入院而找不到任何原因的新生儿占 12 0例高胆新生儿的 19.2 % ,与高胆低出生体重儿的 HCMV- DNA阳性率分别为43.5 % ,36 .8%。结论 :部分未明原因的高胆新生儿和高胆低出生体重儿为

To assess the state of infecting human cyto megalovirus(HCMV) among neonate with hyperbilirubinemia.Design:HCMV DNA in urine and blood from one hundred and twenty neonates with hyperbilirubinemia were detected by polymerase chain reacion (PCR) technique,aged 12 to 28 days.Results showed that Most pathogeny of 120 cases are light weight at birth,asphyxia at birth or infection,their positive rate of HCMV PCR DNA respectively are 36.8%(7/19),3.1%(1/32) 8.1%(3/37).32 cases(19.2%) couldn't be found anything pathogeny.it's positive rate of HCM PCR DNA is 43.5%(10/23).Thenefosg art of neonates with hyperbilirubinemia that couldn't be found anything pathogeny and neonates of light weight at birth with hyperbilirubinemia are infected with human cytomegalovirus. (Original article in page 118)