摘要
目的检测急性心肌梗死（AMI）患者治疗前后血清中脂蛋白a[Lp（a）]、同型半胱氨酸（HCY）和c-反应蛋白（CRP）的变化情况。方法采用生物化学方法测定60例试验组及30例对照组外周血中LP（a）、HCY和CRP的含量。结果AMI患者LP（a）、HCY和CRP均显著高于对照组（P=0．001、P：0．001和P=0．007）；AMI患者治疗后HCY和CRP浓度显著下降（P=O．001），Lp（a）治疗前、后差异无统计学意义（P=0．731）。结论高Lp（a）和HCY与AMI的发生有关，两者与CRP同时检测可以作为AMI的预防和疗效观察的辅助指标。
Objective To explore the changes of serum lipoprotein a [ Lp（a） ], homocysteilne （HCY） and c - reactive protein （CRP） in acute myocardial infarction （AMI） patients before and after treatment. Methods Biochemical method was used to detect the content of LP（a）, Hcy and CRP in peripheral blood within experiment groups（60 cases） and control groups（30 cases）. Results The contents of LP（a） ,HCY and CRP in AMI patients are obviously higher than those in control group, （ P = 0.001, P = 0. 00 1和 P = 0. 007） ;after treatment, HCY and CRP concentrations decreased markedly in AMI patients （P = 0.001）. As for Lp（a） there was no significant difference after treatment. Conclusion There is a relationship between high Lp（a）,Hcy and the occurring of AMI. The former two detected simultaneously with CRP can be used as the auxiliary indicators in preventing AMI and observing its curative effect.
出处
《医学检验与临床》
2012年第5期16-17,共2页
Medical Laboratory Science and Clinics
