期刊文献+

左肺结核伴纵隔淋巴结结核经^(18)氟-脱氧葡萄糖正电子发射断层扫描术误诊肺癌淋巴结转移 被引量:3

Le Pulmonary and Mediastinal Lymphnode Tuberculosis Misdiagnosed as Lymphatic Metastasis from Lung Cancer on 18- uoro-deoxy-glucose-positron emission tomography
原文传递
导出
摘要 目的探讨结核病在18氟-脱氧葡萄糖(18F-FDG)正电子发射断层扫描术(PET)中的影像学表现,提高对PET/CT在肺部包块诊断作用的认识,减少误诊。方法回顾分析2010年3月收治的1例肺结核合并纵隔淋巴结结核病患者的误诊及诊断治疗经过,分析误诊原因并总结诊治经验,结合文献复习肺部包块在PET/CT中的表现及临床特点。结果患者为肺部包块伴纵隔淋巴结包块,胸部CT提示肺癌伴纵隔淋巴结转移,PET/CT也考虑左肺下叶肺癌伴淋巴结转移。最后经纵隔镜淋巴结活检确诊结核,并抗结核治疗好转。结论结核等感染性疾病常可导致18F-FDG的摄取增加而造成PET/CT阳性结果,因此在18F-FDG PET/CT呈现阳性结果时须注意鉴别病变良恶性,其中高标准摄入值包块尤其需要注意与结核病相鉴别。 Objective To explore the imaging finding of tuberculosis in 18-fluoro-deoxy-glucose (18F-FDG)-positron emission tomography (PET) and enhance the cognition to the diagnostic role of PET/CT on pulmonary mass to reduce misdiagnosis. Methods We reviewed the process ofmisdiagnosis, diagnosis and treatment in one patient with pulmonary and mediastinal lymphnode tuberculosis treated in 2010, analyzed the misdiagnosis reasons, and summarized the experiences of diagnosis and treatment. Furthermore, related literatures were reviewed on PET/CT imaging findings and clinical characteristics of pulmonary masses. Results The patient presented with pulmonary mass with mediastinal lymphnode mass. Both chest CT and PET/CT suggested lung cancer in left lobus inferior pulmonis with mediastinal lymph node metastasis. Finally, tuberculosis was confirmed by lymphnode biopsy through mediastinoscope and alleviated after anti-tuberculosis therapy. Conclusions Tuberculosis and other infectious diseases may lead to the increasing uptake of 18F-FDG, which can cause a positive result in PET/CT. Accordingly, we should distinguish between benign and malignant lesions when 18F-FDG PET / CT shows positive results. Especially, the high-standardized uptake value mass should be distinguished from tuberculosis.
出处 《华西医学》 CAS 2012年第10期1474-1477,共4页 West China Medical Journal
关键词 结核 正电子发射断层扫描 18氟-脱氧葡萄糖 Tuberculosis Positron emission tomography 18F-Deoxyglucose
  • 相关文献

参考文献17

  • 1Spiro SG, Niederman M, Yew WW, et al. Year in review 2009: respiratory infections, tuberculosis, pleural diseases and lung cancer[J]. Respirology, 2010, 15(3): 562-572.
  • 2杨明,储成凤,刘斌,方丽,徐秋贞,姚青,郭庆明,滕皋军.非钙化型肺结核瘤的动态CT增强研究[J].东南大学学报(医学版),2006,25(6):448-451. 被引量:4
  • 3Tateishi U, Kusumoto M, Akiyama Y, et al. Role of contrast- enhanced dynamic CT in the diagnosis of active tuberculoma[J]. Chest, 2002, 122(4): 1280-1284.
  • 4Christensen JA, Nathan MA, Mullan BP, et al. Characterization of the solitary pulmonary nodule: 18F-FDG PET versus nodule-enhancement CT[J]. AJR Am J Roentgenol, 2006, 187(5): 1361-1367.
  • 5Zhuang H, Alavi A. 18 Fluorodeoxyglucose positron emission tomographic imaging in the detection and monitoring of infectionand inflammation[J]. Semin Nucl Med, 2002, 32(1): 47-59.
  • 6Strauss LG. Fluorine-18 deoxyglucose and false-positive results: a major problem in the diagnostics of oncological patients[J]. Eur J Nucl Med, 1996, 23(10): 1409-1415.
  • 7Forstrom LA, Dunn WL, Mullan BP, et al. Biodistribution and dosimetry of [(18)F]fluorodeoxyglucose labelled leukocytes in normal human subjects[J]. Nucl Med Commun, 2002, 23(8): 721- 725.
  • 8Goo JM, Im JG, Do KH, et al. Pulmonary tuberculoma evaluated by means of FDG PET: findings in 10 cases[J]. Radiology, 2000, 216(1): 117-121.
  • 9Kostakoglu L, Agress H Jr, Goldsmith SJ. Clinical role of FDG PET in evalutaion of cancer patients[J]. Radiographics, 2003, 23(2): 315- 340.
  • 10Chang JM, Lee H J, Goo JM, et al. False positive and false negative FDG-PET scans in various thoracic diseases[J]. Korean J Radiol, 2006, 7(1): 57-69.

二级参考文献29

  • 1中华医学会结核病学分会第七届委员会名单[J].中华结核和呼吸杂志,2004,27(12):800-800. 被引量:7
  • 2储成凤,杨明,徐秋贞,陈峰,朱亚彬,姚青,张俭.同层动态CT增强扫描对2cm内肺癌及肺结核球的价值[J].现代医学,2004,32(6):371-374. 被引量:4
  • 3刘斌,杨明,储成凤,徐秋贞,朱晓莉,姚青,张俭.血管纠集征的CT研究[J].东南大学学报(医学版),2005,24(4):240-243. 被引量:2
  • 4李连弟,鲁凤珠,张思维,牧人,孙秀娣,皇甫小梅,孙杰,周有尚,欧阳宁慧,饶克勤,陈育德,孙爱明,薛志福,夏毅.中国恶性肿瘤死亡率20年变化趋势和近期预测分析[J].中华肿瘤杂志,1997,19(1):3-9. 被引量:869
  • 5Shreve P D,Radiology,1998年,207卷,431页
  • 6SWENSEN S J,BROWN L R,SCHUELER B A,et al.Solitary pulmonary nodule:CT valuation of enhancement iodinated contrast material:a preliminary report[J].Radiology,1992,82(2):343-347.
  • 7YAMASHITA K,MATSUNODE S,TAKAHASHI R,et al.small peripheral lung carcinoma evaluated with incremental dynamic CT:radiology pathologic correlation[J].Radiology,1995,196(2):401-408.
  • 8TATEISHI U,KUSUMOTO M,AKIYAMA Y,et al.Role of contrast-enhanced dynamic CT in the diagnosis of active tuberculoma[J].Chest,2002,122(4):1280-1284.
  • 9SWENSEN S J,VIGGIANO R W,MIDTHUN D E,et al.Lung nodules enhancement at CT:multicenter study[J].Radiology,2000,214(1):73-80.
  • 10Peto R;Darby S;Deo H.1950年以来英国的吸烟、戒烟和肺癌状况: 全国统计和两项病例对照研究的综合报告[J]英国医学杂志中文版,2000(04).

共引文献88

同被引文献29

引证文献3

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部