期刊文献+

急性脑梗死中同型半胱氨酸及其脂质代谢的检测分析 被引量:1

Detection of Homocysteine and Lipid Metabolism in Acute Cerebral Infarction
下载PDF
导出
摘要 目的观察急性脑梗死患者血浆同型半胱氨酸(Hcy)及血脂水平,探讨Hcy及血脂水平与急性脑梗死发生的关系。方法采用测定106例急性脑梗死患者治疗前后以及100例健康者(对照组)血浆Hcy及血脂浓度。结果急性脑梗死组血浆Hcy和LDL含量明显高于对照组(P<0.001);GLU,HDL,TG,TC含量与对照组比较无统计学意义(P>0.05);急性脑梗死患者治疗后的血浆Hcy含量显著下降(P>0.05)。结论血浆同型半胱氨酸可以作为急性脑梗死的诊断和疗效观察的辅助指标。 Objective To investigate the plasma homocysteine and lipid level in patients with acute cerebral infarction and to explore the significances of diagnosis and therapeutic effect.Methods Plasma homocysteine and lipid level of 100 normal subjects and 106 cases of acute cerebral infarction patients before and after treatment were detected by Biochemical analyzer.Results Plasma homocysteine and LDL level in acute cerebral infarction patient group were higher than that in control group(P 0.001),the difference was extremely significant,Compared with the control group,the difference of GLU,HDL,TG,TC were no significant(P0.05),the homocysteine level decreased significantly in acute cerebral infarction patients after treatment,there was significant difference(P0.001) Conclusion Hyperhomocysteine is associated with the occurrence of acute cerebral infarction,and plasma homocysteine levels can be as the aid index for the diagnosis and therapeutic observation to acute cerebral infarction.
出处 《中国医药指南》 2012年第29期51-52,共2页 Guide of China Medicine
关键词 同型半胱氨酸血症 急性脑梗死 脂质代谢 Homocysteine Acute cerebral infarction Lipid
  • 相关文献

参考文献4

二级参考文献23

  • 1吴青,刘春风.血同型半胱氨酸水平与动脉粥样硬化性脑梗死的关系[J].苏州大学学报(医学版),2005,25(2):332-334. 被引量:8
  • 2Sun Y,Chien K,Hsu H,et al.Use of serum homocysteine to predict stroke,coronary heart disease and death in ethinic Chinese-12-year prospective cohort study[J].Circ J,2009,73(8):1423-1430.
  • 3Christen WG,Ridker PM.Blood levels of homocysteine and atherosclerotic vascular disease[J].Curr Atheroscler Rep,2000,2(3):194-199.
  • 4Selhub J,Dangelo A.Relationship between homocysteine and thrombotic disease[J].Am J Med Sci,1998,316(2):129-141.
  • 5Giles WH,Croft JB,Greenlund KJ,et al.A risk factor for vascular disease:hyperhomocysteinemia[J].Stroke,2003,29(12):473-477.
  • 6Tantirittisak T,Sura T,Moleerergpoom W,et al.Plasma homocysteine and ischemic stroke patients in Thailand[J].J Med Assoc Thai,2007,90(6):1183-1187.
  • 7Faraci FM,Lentz SR.Hyperhomocysteinemia,oxidative stress and cerebral vascular dysfunction[J].Stroke,2004,35(12):345-347.
  • 8Riba R,Nicobou A,Troxler M,et al.Altered platelet reactivity in peripheral vascular disease complicated with elevated plasma homocysteine levels[J].Atherosclerosis,2004,175(1):69-75.
  • 9Malinow MR,Bostom AG,Krauss RM.Homocystine,diet,andcardiovascular diseases.A statement for healhcare profession fromthe Nutrition Commitee,American Heart Association.Circution,1999,99:178-182.
  • 10McCully KS.Vascular pathology of homocysteine:implication for the pathogenesis of arteriosclerosis.Am J Patho,1996,56:111-128.

共引文献11

同被引文献14

引证文献1

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部