皮肤类胡萝卜素水平和代谢综合征的关系分析

Relationship between skin carotenoid level and metabolic syndrome related indices

目的分析皮肤类胡萝卜素水平与代谢综合征（MS）相关指标的关系。方法对象为2010年12月至2011年12月陕西省人民医院体检中心体检人群493人（男257人，女236人），年龄（49±14）岁。测量其皮肤类胡萝卜素水平，并检测MS相关指标如甘油三酯、高密度脂蛋白胆固醇、血压、空腹血糖、腰围等。每一个指标作为一个危险因素，没有危险因素的为正常组，仅有1个危险因素的为低危组，有2个危险因素的为高危组，符合诊断标准的为MS组。结果正常组（103例）、低危组（63例）、高危组（172例）、MS组（155例）皮肤类胡萝卜素指数分别为40407±10961、28396±8683、28523±8887、23303±8887，各组间差异有统计学意义（F=72．704，P〈0．01）；性别与皮肤类胡萝卜素水平有明显的相关性，男性明显低于女性（P〈0．01）；年龄与皮肤类胡萝卜素水平没有相关性（P〉0．05）。结论皮肤类胡萝卜素水平与MS有负相关性，测量皮肤类胡萝卜素水平对预防MS起到一定的作用。

Objective To provide scientific rationales through an analysis of the relationship between skin carotenoid level and metabolic syndrome related indices so as to prevent the occurrences of metabolic syndrome （MS）. Methods A total of 493 cases from December 2010 to December 2011 were recruited to measure the skin carotenoid levels and various laboratory indices of metabolic syndrome. Results Along with the rising risk factors of MS, the skin carotenoid level declined. And there were significant differences between the normal group（n = 103）, low risk group（n =63）, high risk group （n = 172） and the MS group（n = 155 ） （40 407 ± 10 961,28 396 ± 8683,28 523 ±8887, 23 303 ±8887, F = 72. 704, P 〈 0. 01 ）. Gender and skin carotenoid level had an obvious correlation. Males were significantly lower in females （P 〈 0. 01 ）. There was no correlation of age and skin carotenoid level （P 〉 0. 05 ）. Conclusions Skin carotenoid level and metabolic syndrome have a negative correlation. Measurement of skin carotenoid level plays a certain role in the prevention of metabolic syndrome.