自噬在肿瘤发生、发展、治疗及预后中的作用

The role of autophagy in tumourgenesis,development,treatment and prognosis

自噬在肿瘤细胞存活中扮演一把"双刃剑"的作用,它既可以促进细胞生存,也可以导致肿瘤细胞发生自噬性细胞死亡。最近研究表明,自噬在肿瘤的发生、发展、治疗及预后中均扮演重要角色,并有可能成为肿瘤治疗的新途径。

Autophage,just like a＂double-edged sword＂,plays a role in tumor cell survival.With it,tumour cell survival can be promoted,as well as autophagic cell death can be resulted in.Recent research shows that autophage plays an important role in tumourgenesis,development,treatment and prognosis,and it may be a new approach to cancer therapy.