肺门型Castleman病4例报告

Pulmonary Hilum Castleman's Disease: a Report of 4 Cases and Review of Literature

目的回顾性分析肺门型Castleman病的临床资料,旨在提高对肺门型Castleman病的诊断和治疗有效性,减少误诊。方法结合4例临床报告,总结自1992年1月至2011年9月文献报道的肺门型Castleman病6例,对其病程、肿块部位、影像学特征、手术方法及治疗效果进行分析。结果①发病率与性别和年龄无关;②病程长短不一、临床症状不典型,常为体检发现;③胸部CT为最常用和最有价值的诊断方法,多表现为靠近肺门的软组织肿块影;④术前均不能明确诊断;手术以肿块切除及相应肺下叶切除为主;⑤局灶型肺门Castleman病组织学以透明细胞型为主,预后好。结论肺门型Castleman病易误诊为肺癌,手术是诊断和治疗的主要方法,且外科治疗预后好。

Objective To investigate the clinical characteristics of pulmonary hilum Castleman＇s disease. Methods The clinical characteristics of 4 patients diagnosed with pulmonary hilum Castleman＇s disease in our department were analysed and compared with findings in relevant literature. Results Gender and age were not associated with Castleman＇s disease. The disease was often identified in physical examinations with atypical clinical symptoms. Chest CT was the most common and valuable diagnostic method revealing soft tissue mass near the pulmonary hilum. Gross-total resection of the tumor and （or） lobectomy through a combined posterior trans-thoracic approach were commonly performed, with good prognosis. Conclusion Hilum Castleman＇s disease can be effectively diagnosed and treated.