中国人群生理性肺动脉瓣反流的调查分析

Analysis on physiological pulmonary regurgitation in Chinese detected with Doppler echocardiography

目的探讨中国人群生理性瓣膜反流的发生率、在人群中的分布特点以及超声多普勒特征。方法以山东大学齐鲁医院2010年1—6月1750名接受超声心动图检查且无心脏病病史的受检者为调查对象,记录各个瓣膜生理性反流的发生率,观察肺动脉瓣反流的彩色多普勒特征,用连续多普勒测量其最大反流压差。结果生理性肺动脉瓣反流的检出率最高,为30.86%(540/1750),其次为三尖瓣、二尖瓣及主动脉瓣生理性反流,分别为14.63%(256/1750)、7.37%(129/1750)和2.06%(36/1750)。生理性肺动脉瓣反流在1～19岁组及≥60岁组人群中的发生率较高(P<0.05);其在男女人群中的发生率差异无统计学意义(P>0.05);在有生理性三尖瓣反流的人群中的发生率为39.06%(100/256),高于其在总体人群中的发生率(540/1750,30.86%,P<0.05)。连续多普勒测得生理性肺动脉瓣反流的最大反流压差为(7.60±3.90)mmHg。结论生理性肺动脉瓣反流的超声多普勒特征和在人群中的发生率分布有一定特点;最大反流压差对诊断生理性肺动脉瓣反流有一定参考价值。

Objective To observe the prevalence of physiological valvular regurgitation in Chinese, and to analyze the dis tribution characteristics of physiological pulmonary regurgitation （PR） in the crowd, Methods Totally 1750 subjects with out cardiac diseases from Qilu Hospital of Shandong University underwent echocardiography. Incidence of all physiological valvular regurgitation was recorded, and color-Doppler echocardiographic characteristics of physiological PR were observed. The maximum regurgitation pressure of physiological PR was measured by continuous-wave Doppler. Results The preva- lence of physiological PR was 30. 86% （540/1750）, which was the highest in the crowd, followed by tricuspid regurgita tion （256/1750, 14.63%）, mitral regurgitation （129/1750, 7.37%） and aortic regurgitation （36/1750, 2.06%）. The in cidence of physiological PR was much higher in people 〈20 years old and ≥60 years old （P〈0.05）, while there was no significant difference between men and women （P〉0.05）. Meanwhile, the prevalence of physiological PR in those with tricuspid regurgitation （TR） was 39.06% （100/256）, was higher than the overall prevalence （540/1750, 30.86%, P〈 0. 05）. The maximum regurgitation pressure of physiological PR measured by continuous-wave Doppler was （7.60± 3.90）mmHg. Conclusion Doppler eehocardiographic characteristics and distribution of physiological valvular regurgitation physiological PR are special. The maximum regurgitation pressure may be used as a reference for assessing physiological PR.