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妊娠期梅毒70例临床分析 被引量:6

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摘要 目的:探讨妊娠期梅毒患者妊娠结局的影响因素。方法:回顾性分析70例妊娠期梅毒患者按首次筛查时的孕周(是否>孕28周)、分娩时的血清TRUST滴度(是否<1∶8)及有无进行规范治疗进行分组,分析梅毒孕产妇的妊娠结局情况。结果:①筛查孕周<28周组先天梅毒的发生率为5.36%(3/56);孕周≥28周组先天梅毒的发生率为35.71%(5/14),两组比较,差异有统计学意义(P<0.05)。②分娩时孕母的血清TRUST滴度<1∶8组先天梅毒的发生率为2.04%(1/49);滴度≥1∶8组先天梅毒的发生率为53.85%(7/13),两组比较,差异有统计学意义(P<0.05)。③规范治疗组发生不良妊娠结局者占5.00%(2/40),未治疗组占73.33%(22/30),两组比较,差异有统计学意义(P<0.05);两组先天梅毒的发生率分别为2.50%(1/40)和23.33%(7/30),两组比较,差异有统计学意义(P<0.05)。结论:梅毒孕产妇未早期筛查、分娩时血清学TRUST滴度高(滴度≥1∶8)及未规范治疗是发生先天梅毒等不良妊娠结局的重要因素。
出处 《中国妇幼保健》 CAS 北大核心 2012年第31期4881-4883,共3页 Maternal and Child Health Care of China
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  • 1Genc M, Ledger WJ. Syphilis in pregnancy[J]. Sex Transm Infect, 2000, 76 (2) : 73-79.
  • 2Wendel GD, Sheffield JS, Hollier LM et al. Treatment of syphilis in pregnancy and prevention of congenital syphilis[J]. Clin Infect Dis, 2002, 35 (2) : 200-209.
  • 3CDC. Sexually transmitted diseases treatment guidelines 2006[J] .MMWR, 2006, 55 (RR-11): 1-94.
  • 4鲁东平,王芬,张荣,李湘辉,梁瑞.深圳市宝安区2008-2009年孕产妇及新生儿梅毒患病情况分析[J].中国皮肤性病学杂志,2011,25(3):212-214. 被引量:38
  • 5张荣莲,陈烈平,陈起燕,王秀云,张丽萍,修晓燕,赵秀艳.339例妊娠期梅毒母婴传播的干预研究[J].中华流行病学杂志,2006,27(10):901-904. 被引量:24
  • 6Webber MP, Lambert G, Bateman DA et al. Maternal risk factors for congenital syphilis: a case - control study [J]. Am J Epidemiol, 1993, 137 (4) : 415-422.
  • 7Tikhonova L, Salakhov E, Southwick K et al. Congenital sy - philis in the Russian Federation : magnitude, determinants, and consequences[J]. Sex Transm Infect, 2003 ;, 79 (2) : 106 - 110.
  • 8周华,潘鹏,洪福昌,陈钢,杨帆,林丽君,蔡于茂.胎传梅毒危险因素的病例对照研究[J].中华皮肤科杂志,2006,39(12):681-684. 被引量:17
  • 9Watson -Jones D, Changalucha J, Gumodoka Bet al. Syp.h - ilis in pregnancy in Tanzania. I. Impact of maternal syphilis on outcome of pregnancy [J]. J Infect Dis, 2002, 186 (7): 940 - 947.
  • 10Goh BT, Thomton AC. Antenatal screening for syphilis [J].Sex Transm Infect, 2007, 83 (5) : 345 - 346.

二级参考文献27

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同被引文献68

  • 1朱慧兰,谷进,苏向阳,赖维.妊娠梅毒孕期内和妊娠前抗梅毒治疗对分娩结果的影响[J].中山大学学报(医学科学版),2006,27(2):200-202. 被引量:13
  • 2Hawkes S,Matin N,Broutet N,et al.Effeetiveness of interventions to im-prove screening for syphilis in pregnancy:a systematic review and me-ta-analysis[J].Lancet Infect Dis,2011,11(9):684-691.
  • 3Hong FC,Liu JB,Feng TJ,et al.Congenital Syphilis:An Economic Evalu-ation of a Prevention Program in China[J].Sex Transm Dis,2010,37(1):26-31.
  • 4Katinka ponyai,Eszter Otorhazi,Marta Marschalta karpati and Ferenc Rozgonyi.Syphi-lis:today[J].Rev Med Microbiol,2010,21(4):84-95.
  • 5Cheng JQ,Zhou H,Hong FC,et al.Syphilis screening and intervention in 500 000 pregnant women in Shenzhen,the people's Replublic of China [J].Sex Transm Inf,2007,83(5):347-350.
  • 6Zhu LP,Qin M,Du L,et al.Maternal and congenital syphilis in Shanghai,China,2002 to 2006[J].Int J Infect Dis,2010,14Suppl e45-48.
  • 7Blencowe H,Cousens S,Kamb M,et al.Lives Saved Tool supplement de-tection and treatment of syphilis in pregnancy to reduce syphilis relat-ed stillbirths and neonatal mortality[J].BMC Public Health,2011,13(11 suppl 3):S9.
  • 8Kuznik A,Lamorde M, Nyabigambo A,et al. Antenatal syphilis screening using point - of - care testing in Sub - Saharan African countries : a cost — effectiveness analysis[ J]. PLoS Med, 2013,10(11) :el001545.
  • 9Gomez GB,Kamb ML,Newman LM,et al. Untreated maternal syphilis and adverse outcomes of pregnancy : a systematic review and meta - analysis[ J]. Bull World Health Organ, 2013,91 (3) : 217 -226.
  • 10Centers for Disease Control and Prevention, Workwski KA, Beronan SM. Sexually transmitted diseases treatment guidelines 2006 [J] .MMWR Recomm Rep, 2006, 55 ( RR-11): 1 - 94.

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