摘要
采用钛基锡锑(Ti/Sb-SnO2)电极对透明质酸(HA)进行电化学降解研究,考察了电解时间、电流密度、温度、HA初始浓度、乙酸钠电解质浓度等因素对降解效果的影响,并对降解产物进行了表征。结果表明,Ti/Sb-SnO2电极的降解效果随电解时间、电流密度和温度的增加而提高,随HA初始浓度、乙酸钠浓度的增大而降低。Ti/Sb-SnO2电极降解基本不改变产物的结构和葡萄糖醛酸含量,只在其端基位置生成C=O双键。HA的断链位置可能位于其主链上的糖苷键。
The electrochemical degradation of hyaluronan （HA） using Ti/Sb-SnO2 electrode was studied. The effect of different conditions such as electrolysis time, current density, temperature, initial concentration of HA, and concentration of sodium acetate was investigated and the degradation products were characterized. The results show that the effect of HA degradation using Ti/Sb-SnO2 electrode increases with electrolysis time expanding, current density and the temperature increasing, decreases with the initial concentration of HA and the concentration of sodium acetate increasing. In this degradation process using Ti/Sb-SnO2 electrode, the chemical structure and the content of glucuronic acid of degraded HA were not obviously modified besides C = O groups formed at the end group of degraded HA. The chain scission position might locate at the glycosidic bonds of HA main chain.
出处
《高分子材料科学与工程》
EI
CAS
CSCD
北大核心
2012年第11期100-104,共5页
Polymer Materials Science & Engineering
