心型脂肪酸结合蛋白在急性非ST抬高心肌梗死早期鉴别诊断中的价值

The Value of Heart-type Fatty Acid Binding Protein in the Differential Diagnosis of Patients with Acute non-ST Elevation Myocardial Infarction

目的探讨心型游离脂肪酸结合蛋白在急性非ST抬高心肌梗死超早期(<6h)的应用价值。方法选取2009年6月至2012年3月我院就诊的106名NSTEMI患者,以冠状动脉造影结果、冠状动脉CTA结果作为最终诊断,入院即刻定性测定H-FABP及定量测定cTnI。结果在本研究入组的患者中,H-FABP、cTnI相比具有较好的敏感性和特异性;同时检测H-FABP与cTnI两项诊断NSTEMI,均有较高敏感性、特异性、阳性预测值、阴性预测值。结论 H-FABP可作为急性心肌损伤检测的一项快速、准确、敏感、特异的指标。

Objective To explore the application value of H-FABP in NSTEMI early diagnosis.Methods 106 NSTEMI patients in our hospital from 2009.3 to 2012.3 were selected with PCI,CTA results as the diagnostic criteria.Then H-FABP and cTnI were collected in early period of NSTEMI.Results Compared with cTnI,H-FABP showed higher sensitivity and specificity,and combining H-FABP with cTnI,the sensitivity,specificity,positive and negtive predictive values indicated the combination had the highest value in diagnosis of NSTEMI.Conclusion H-FABP is one of the most useful methods in the early diagnosis of NSTEMI.