期刊文献+

奥美拉唑联合阿莫西林及甲硝唑治疗幽门螺杆菌感染82例临床效果观察 被引量:3

下载PDF
导出
摘要 目的探讨奥美拉唑联合阿莫西林及甲硝唑治疗幽门螺杆菌感染的临床效果。方法将2010年4月至2012年4月于我院诊治且确诊为幽门螺杆菌感染行消化道溃疡患者共82例,随机编入观察组(41例)和对照组(41例),其中观察组患者采用奥美拉唑联合阿莫西林及甲硝唑三联疗法,对照组患者仅服用奥美拉唑及甲硝唑,记录治疗后有效率、幽门螺杆菌根除率以及不良反应并进行统计学比较。结果采观察组患者治疗有效共38例(92.68%),幽门螺杆菌根除共27例(65.85%),对照组患者治疗效果有效共28例(68.29%),幽门螺杆菌根除共9例,观察组疗效明显优于对照组(P<0.05)。两组患者不良反应均较轻,且无统计学差异(P<0.05)。结论治疗幽门螺杆菌感染性消化道溃疡时采用奥美拉唑、阿莫西林联合甲硝唑三联疗法疗效较好,且安全性较高,值得临床推广。
作者 吴美娟
出处 《中国医药指南》 2012年第30期130-131,共2页 Guide of China Medicine
  • 相关文献

参考文献4

二级参考文献48

  • 1中国慢性胃炎共识意见[J].胃肠病学,2006,11(11):674-684. 被引量:835
  • 2杨昭徐.益生菌防治幽门螺杆菌感染的作用[J].中华消化杂志,2006,26(12):850-851. 被引量:35
  • 3Ducons JA, Santolaria S, Guirao R, et al . Impact of clarithromycin resistance on the effectiveness of a regimen for Helicobacter pylori: a prospective study of 1-week lansoprazole, amoxycillin and clarithromycin in active peptic ulcer. Aliment Pharmacol Ther, 1999,13: 775-780.
  • 4Scaccianoce G, Hassan C, Panarese A, et al. Helicobacter pylori eradication with either 7-day or 10-day triple therapies, and with a 10-day sequential regimen. Can J Gastroenterol, 2006,20:113-117.
  • 5Zullo A, Gatta L, De Francesco V, et al. High rate of Helicobacter pylori eradication with sequential therapy in elderly patients with peptic ulcer: a prospective controlled study. Aliment Pharmacol Ther, 2005,21:1419-1424.
  • 6Vaira D, Zullo A, Vakil N, et al. Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a randomized trial. Annals of Internal Medicine, 2007,146:556-563.
  • 7[2]Malfertheiner P,Megraud F,O'Morain C,et al.Current concepts in the management of Helicobacter pylori infection:the Maastricht Ⅲ Consensus Report.Gut,2007,56:772-781
  • 8[3]Moayyedi P,Deeks J,Talley NJ,et al.An update of the Cochrane systematic review of Helicobacter pylori eradication therapy in nonulcer dyspepsia:resolving the discrepancy between systematic reviews.Am J Gastroenterol,2003,98:2621-2626
  • 9[4]Talley NJ,Vakil NB,Moayyedi P.American gastroenterological association technical review on the evaluation of dyspepsia.Gastroenterology,2005,129:1756-1780
  • 10[6]Madisch A,Miehlke s,Neuber F,et al.Healing of lymphocytic gastritis after Helicobacter pylori eradication therapy-a randomized,double-blind,placebo-controlled multicentre trial.Aliment Pharmacol Ther,2006,23:473-479

共引文献63

同被引文献22

引证文献3

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部