2002-2010年闸北区中心医院药品不良反应报告回顾性分析

Retrospective Analysis of Adverse Reaction Reports in Central Hospital of Zhabei District from 2008 to 2010

目的:了解上海市闸北区中心医院药品不良反应(ADR)的表现及其发生特点,促进临床合理用药。方法:对我院2008～2010年收集的383例ADR进行回顾性分析。结果:由抗感染药物导致的ADR最多,共276例,占总数的67.15%;ADR临床表现以皮肤及其附件损害最常见,共275例,占总例数的71.80%。结论:应重视ADR报告和监测工作,合理用药,避免或减少ADR发生。

Objective： To understand the expression and characteristic of adverse drug reactions （ADR） occurrence in Central Hospital of Shanghai Zhabei District for promoting rational drug use. Methods ： 383 cases reported and collected in our hospital from 2008 to 2010 were retrospectively analyzed. Results ： Most of ADRs were induced by anti-infectives, accounting for 67.15% （276 cases）. The injuries of skin and accessories were most common, accounting for 71.80% （275 cases）. Conclusion ： ADR monitoring should be attached importance in clinic. Agents should be rationally used to prevent or reduce the occurrence of ADR.