量子点给药载体研究进展

Quantum Dots-Based Drug Delivery System

量子点因其优良的发光性质,易于修饰的表面结构,在化学、医学和材料等研究领域显示了极其广阔的应用前景,受到科研工作者越来越多的关注。本文介绍了量子点的独特光学性质、制备方法、水溶性修饰和量子点与生物分子的偶联,重点讨论了量子点作为给药载体和给药载体标记物,以及以量子点为平台建立的多功能纳米给药体系的近年研究进展,阐述了当前研究中的主要发展方向和仍需解决的问题。

Fluorescent semiconductor quantum dots have shown great potential applications in analytical chemistry, biochemistry and biomedicine. The unique optical properties and various surface structures of QDs have received more and more intensive attention. Here,we present a review of current development in QDs, including their synthetic method, surface modification and bioconjugation, especially their applications in drug delivery.