伊犁地区哈萨克族食管癌高低发区人体内外环境化学元素含量分析

Comparative study on concentrations of chemical trace elements in human body and environment between high risk and low risk areas of esophageal cancer in Yili Kazakh

目的从土壤中化学元素含量分布及人体组织中化学元素的富集规律,探讨伊犁地区哈萨克族食管癌高发与地球化学元素的关系,为新疆哈萨克族食管癌的防治工作提供科学依据。方法采用GGX-6A型原子吸收分光光度计测定伊犁地区哈萨克族食管癌高发区新源县和低发区巩留县土壤和当地居民头发中铁(Fe)、铜(Cu)、锌(Zn)、锰(Mn)、钼(Mo)、镉(Cd)、铅(Pb)、硒(Se)、铬(Cr)和镍(Ni)元素含量。结果 (1)新源县土壤中Fe、Cu、Mn、Mo、Cd和Pb元素含量高于巩留县,差异具有统计学意义(P<0.05);而Zn元素含量低于巩留县,差异具有统计学意义(P<0.05);(2)新源县居民头发中Cd元素含量高于巩留县,差异具有统计学意义(P<0.05);而Fe、Zn和Se元素含量低于巩留县,差异具有统计学意义(P<0.05);(3)新源县与巩留县居民头发与土壤中化学元素丰度值曲线基本吻合,人体内环境与外环境密切相关。结论地球化学元素含量的差异性分布可能是伊犁地区哈萨克族食管癌高发的重要因素之一。

Objective To investigate the correlation of chemical elements concentrations in the soil and human tissue with the high incidence of esophageal cancer in Yili kazakh , so providing the evidences for the prevention of esophageal cancer in Yili Kazakh.Methods Iron , copper , manganese , nickel , zinc , cadmium , selenium , chrome , molybdenum and lead contents in the soil and the residents＇hair were detected in a high risk area of esophageal cancer in Xinyuan County , and a low risk area of Gongliu County by GGX-6A atomic absorption spectrophtometer.Results （ 1 ） The concentrations of iron , copper , manganese and nickel in the soil of Xinyuan County were significantly higher than those of Gongliu County （ P 0.05 ）; （ 2 ） The concentrations of cadmium in the residents′hair of Xinyuan County was significantly higher than Gongliu County （ P 0.05 ）, while the concentrations of iron , zinc and selenium were lower （ P 0.05 ）; （ 3 ） The chemical element abundant value curve of the residents′hair and the soil in Xinyuan County and Gongliu County were consistent with each other , the human body environment is closely related to the external environment.Conclusion The difference of chemical trace elements concentrations in the soil may be one of the important factors of the high incidence of esophageal cancer in Yili kazakh.