胰腺脂肪浸润与胰岛素抵抗关系的临床与CT分析

Relationship between insulin resistance and fatty pancreas:A clinical and CT analysis

目的探讨胰腺脂肪浸润与胰岛素抵抗(IR)之间的关系。方法采用多层螺旋CT(MSCT)对所有研究对象进行上腹部扫描并分析其临床资料,将60例胰腺脂肪浸润患者与对照组对比研究,观察IR的发生情况。结果胰腺脂肪浸润组与对照组相比较,IR的发生率有显著性差异(P<0.01)。结论胰腺脂肪浸润患者存在明显脂代谢紊乱,临床表现为胰腺脂肪浸润,提示胰腺脂肪浸润与IR彼此之间存在着相互发生和发展的作用。

Objective To study the relationship between fatty pancreas and insulin resistance （IR）. Methods Multi-level spiral CT （MSCT） was employed to scan the upper abdomens of all re- search participants and their clinical data were retrospectively analyzed. Sixty patients with fatty pan- creas were included in the study group, which was compared with the control group to observe the inci- dence of IR. Results Compared with the control group, the incidence of IR in the study group showed significant difference （P 〈 0.01 ）. Conclusion Patients with pancreatic fatty infiltration have obvious lipid metabolism disorders. The clinical manifestations of the fatty pancreas include pancreatic fatty infiltration, indicating the interactive relationship between the pancreatic fatty infiltration and IR.