390例Ⅰ类切口手术围术期预防使用抗菌药物调查分析

Survey of the precautionary application of antibiotics in 390 clean surgical operations during perioperative period

目的了解Ⅰ类切口手术患者围术期抗菌药物预防应用情况,评价其合理性。方法对2010年6月—2011年7月390例病历进行回顾性调查分析。结果 390例患者中,387例使用了抗菌药物,预防用药率99.2%;术前0.5～2 h首次给药160例,占41.3%;两联用药17例,占5.9%,选用次数最多的为头孢唑啉,其次为头孢米诺、磺苄西林、氨曲南、哌拉西林舒巴坦等;使用疗程最短为1 d,最长为20 d,其中48 h内停药25例,占8.7%,平均使用天数6.9 d。结论本院Ⅰ类切口手术预防性应用抗菌药物存在明显不合理现象,应加强管理。

Objective To investigate precautionary application of antibiotics in type 1 inci- sion operation during perioperative period, and evaluate the rationality. Methods A total of 390 cases from June 2010 to July 2011 were collected and analyzed retrospectively. Results Among the 390 cases, 387 cases received antibiotics. The ratio of preventive medication was 99.2% and 160 cases （41.3 % ） received antibiotics 0.5 2 hours before operations. Two antibiotics were combined in 17 cases （5.9 % ）. Cephazolin was used most frequently followed by cefminox, sulbenicillin, aztreonam and piperacillin sulbactam. The duration of antibiotics intake was between 1 to 20 days and 25 cases （8.7%） stopped medication in 48 h. The average drug intake duration was 6.9 days. Conclusion The application of antibiotics is irrational in type Ⅰ incision operations for precautionary reasons, and management to antibiotics should be strengthened.