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Cullinl蛋白与恶性肿瘤 被引量:1

Cullinl and malignant tumors
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摘要 Cullinl是cullin基因组中的一个成员,Cullinl所组装的复合体具有典型的泛素连接酶活性,介导许多细胞周期蛋白尤其是癌相关蛋白的降解过程,有效地调节着细胞周期进程。Cullinl在恶性肿瘤的发生发展中起到很重要的作用。 Cullinl is a member of the cullin genome. The cullinl assembly complex has typical ubiq- uitin ligase activity, and mediates cell cycle proteins, especially cancer-associated protein degradation process, an then effectively regulates the cell cycle progression. Cullinl play an important role in the genesis and development of malignant tumors.
出处 《国际肿瘤学杂志》 CAS 2012年第11期818-820,共3页 Journal of International Oncology
基金 基金项目:江苏省恶性肿瘤生物标志物与防治重点实验室开放课题(11ZLKF09)
关键词 肿瘤 Cullin1 Neoplasms Cullinl
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