HLA—G蛋白在肿瘤组织及患者血清中的表达及其在肿瘤免疫逃逸中的作用

Expression of HLA-G in serum and tissue of cancer patients and its function in tumor immune escape

随着对人类白细胞抗原G（HLA—G）蛋白作用机制的深入了解，越来越多的研究发现HLA—G与肿瘤的免疫逃逸密切相关。大量研究显示在肿瘤患者的血浆、肿瘤组织中均可检测到HLA—G蛋白、mRNA的表达。

With depth understanding of the mechanism of human leukocyte antigen G （HLA-G） protein, more and more studies have found that HLA-G is closely related with tumor immune escape. Numerous studies have shown that the expression of HLA-G protein and mRNA could be detected in patients with cancer.