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CA199在卵巢良性畸胎瘤诊断中的临床意义 被引量:3

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摘要 目的探讨糖类抗原199(CA199)在卵巢良性畸胎瘤诊断中的临床意义。方法选取2005年4月至2011年4月太仓市中医医院妇产科进行手术治疗并术前行CA199在内的4种肿瘤标记物检测且术后经病理证实为良性畸胎瘤患者68例,对其临床资料进行回顾性分析。结果在4种肿瘤标记物中,CA199的阳性率最高,为33.8%。肿瘤最大径线平均大小为(6.21±3.12)cm。CA199、CA125升高组肿瘤大于正常组(P<0.05);当肿瘤发生于双侧卵巢时,CA199显著升高(P<0.05);患者平均年龄36.7岁,年龄小者CA199阳性率高于年龄大者。结论 CA199在卵巢良性畸胎瘤的诊断和鉴别诊断中具有一定意义。当血清CA199升高时,无论对侧卵巢是否正常,手术时均应仔细检查对侧卵巢。
作者 宋秋瑾
出处 《临床医学》 CAS 2012年第10期76-77,共2页 Clinical Medicine
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  • 1龚晓明,冷金花,郎景和,黄荣丽,刘珠凤,孙大为,朱兰.卵巢成熟畸胎瘤695例临床分析[J].中国医学科学院学报,2004,26(6):692-695. 被引量:51
  • 2申桂华,姜展红,陈德新.血清肿瘤标记物测定在卵巢成熟畸胎瘤及其恶变者的临床应用[J].中国癌症杂志,2006,16(5):370-373. 被引量:7
  • 3连利娟,中华妇产科杂志,1985年,20卷,257页
  • 4Kikkawa F,Ishikawa H,Tamakoshi K,et al.Squamous cell carcinoma arising from mature cystic teratoma of the ovary:a clinicopathologic analysis[J].Obstet Gynecol,1997,89 (6):1017-1022.
  • 5Comerci JT,Licciardi FK,Bergh PL,et al.Mature cystic teratoma:A clinicopathologic evaluation of 517 cases and review of the literature[J].Obstet Gynecol,1994,84 (1):22-28.
  • 6Kawai M,Kano T,Kikkawa F,et al.Seven tumor markers in benign and malignant germ cell tumors of the ovary[J].Gynecol Oncol,1992,45 (3):248-253.
  • 7Kikkawa F,Nawa A,Tamakoshi,et al.Diagnosis of squamous cell carcinoma arising from mature cystic teratoma of the ovary[J].Cancer,1998,82 (11):2249-2255.
  • 8Suzuki M,Tamura N,Kobayashi H,et al.Clinical significance of combined use of macrophage colony-stimulating factor and squamous cell carcinoma antigen as a selective diagnostic marker for squamous cell carcinoma arising in mature cystic teratoma of the ovary[J].Gynecol 0ncol,2000,77 (3):405-409.
  • 9Yoshioka T,Tanaka T.Immunohistochemical and meolecular studies on malignant transformation in mature cystic teratoma of the ovary[J].J Obstet Gynaecol Res,1998,24 (2):83-90.
  • 10Emoto M,Obama H,Hoduchi S,et al.Transvaginal color Doppler ultrasonic characterization of benign and malignant ovarian cystic teratomas and comparison with serum squamous cell carcinoma antigen[J].Cancer,2000,88 (10):2298-2304.

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  • 1杜晓丽.卵巢成熟囊性畸胎瘤CA199异常升高1例[J].慢性病学杂志,2013,13(12):955-956. 被引量:1
  • 2陈晨,李俊东,黄鹤,冯艳玲,王銮虹,陈亮.肿瘤标志物检测对卵巢成熟、未成熟畸胎瘤的诊断价值[J].癌症,2008,27(1):92-95. 被引量:44
  • 3Kataoka T, Watanabe Y, Hoshiai H. Retrospective evaluation of tumor markers in ovarian mature cystic teratoma and ovarian endometrioma [J]. J Obstet Gynaecol Res,2012,38(8) :1071-1076.
  • 4Emin U,Taflun G,Cantekin I,et al. Tumor markers in mature cystic tera- tomas of the ovary[J]. Arch Gynecol Obstet ,2009,279(2) :145-147.
  • 5Dede M, Gungor S, Yenen MC, et al. CA19-9 may have clinical significance in mature cystic teratomas of the ovary [ J]. Int J Gyne- col Cancer, 2006, 16 (1): 189-193.
  • 6Coskun A, Kiran G, Ozdemir O. CA 19-9 can be a useful tumor marker in ovarian dermoid cysts [ J ]. Clin Exp Obstet Gynecol, 2008, 35 (2): 137-139.
  • 7Atabekoglu C, Bozaci EA, Tezcan S. Elevated carbohydrate antigen 19-9 in a dermoid cyst [J]. Int J Gynaecol Obstet, 2005, 91 (3) : 262-263.
  • 8Kim M J, Kim NY, Lee DY, et al. Clinical characteristics of ovari- an teratoma: age-focused retrospective analysis of 580 cases [ J]. Am J Obstet Gynecol, 2011, 205 (1) : 31-32.
  • 9Kikkawa F, Nawa A, Tamakoshi K, et al. Diagnosis of squamous cell carcinoma arising from mature cystic teratoma of the ovary [ J]. Cancer, 1998, 82 (11): 2249-2255.
  • 10Ito K. CA19-9 in mature cystic teratoma [J]. Tohoku J Exp Med, 1994, 172 (2): 133-138.

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