上腔静脉综合征26例放射治疗的疗效分析

Analysis of therapeutic effect of radiotherapy on 26 patients with superior vena cava syndrome

目的观察放射治疗对肿瘤导致的上腔静脉综合征的疗效。方法对26例肿瘤伴上腔静脉综合征患者均采用放射治疗,放疗用6 mV-X线,开始剂量为每次3.0～4.0 Gy,每天1次,每周5次,3～5次后改为常规分割。结果 26例患者经过治疗完全缓解9例,部分缓解15例,无变化2例,进展0例,总有效率为92.3%。结论放射治疗可作为恶性肿瘤伴上腔静脉综合征治疗的首选方法,放射治疗对肿瘤引起的上腔静脉综合征具有良好的缓解效果,不良反应轻,能有效提高患者的生存质量。

Objective To observe the effect of radiotherapy on superior vena cava syndrome caused by carcinoma. Methods Twenty-six patients with superior vena cava syndrome caused by carcinoma were treated with accelerator 6 mV-X ray. They were first treated with 6 mV-X ray at the dose of 3.0 - 4. 0 Gy a day for three to five fractions, and then with regular dose of fractionated radiation. Results Complete response（ CR） was achieved in 9 patietlts,partial response（ PR） was achieved in 15 patients, no change（NC） in 2 patients, progressive disease （PD） was observed in 0 patients, and the overall effective rate was 92.3%. Conclusion Radiotherapy （：an be used as the first line treatment method for cancer patients with superior vena cava syndrome. Radiotherapy is an effective method in the treatment of superior vena cava syndrome caused by carcinoma, with advan- tages of less side effects and effectively enhancing the patients＇ quality of life.